This is the complete guide to Forensic M.E. Protocol, with all clue locations across every case map laid out for you. To achieve a 100% rating and uncover the full story, you must find every single memory fragment within the victim's dying moments. This guide serves as your master checklist for all nine cases, ensuring no piece of evidence is left behind.

The core of the game is using the M.E. Protocol to dive into a victim's final memories. Inside these memoryscapes, clues manifest as glowing, interactive objects. Finding them all is the only way to fully reconstruct the event and deliver true justice.

First, Some General Advice

Before diving into individual cases, remember these core principles. They apply to every investigation and will help you develop the right mindset.

  • Look High and Low: Many clues are deliberately placed outside your immediate eye-line. Check under tables, on top of shelves, and behind doors. The environment is small, but dense.
  • Interact With Everything: If an object can be picked up, rotated, or opened, do it. A clue might be a note inside a book, a file on a laptop, or an inscription on the bottom of a statue.
  • Listen for Audio Cues: A subtle hum or shimmer often indicates a memory fragment is nearby. Use your ears as much as your eyes.
  • Follow the Light: Memory fragments often emit a faint blue or white glow. In darker environments, scanning the room for these telltale signs can quickly lead you to your next discovery.

Case 1: The First Step

This introductory case is designed to teach you the mechanics, but it's still possible to miss a clue or two if you rush. The victim is found in their apartment.

Living Room Clues

  • Overturned Wine Glass: On the floor near the coffee table. You must inspect it closely.
  • TV Remote: Lying on the sofa cushions.
  • Family Photo: On the mantlepiece. Pick it up and turn it over to find a handwritten note on the back.
  • Laptop: On the coffee table. You need to turn it on and click through two emails.

Kitchen & Body Clues

  • Open Medication Bottle: On the kitchen counter next to the sink.
  • Victim's Mobile Phone: On the floor near the body. Access it to read the last text message received.
  • Cause of Death: Scan the victim's head to identify the fatal wound.
  • Defensive Wounds: Scan the victim's hands and forearms.

Case 2: Echoes of a Struggle

Case 2 introduces more environmental complexity. The scene is a workshop, and the clues are more scattered.

Workshop Floor

  • Bloody Wrench: Located under the main workbench. You'll need to crouch to see it.
  • Security Footage: Access the computer on the desk. You have to rewind the footage to the time of death to log the clue.
  • Overalls: Hanging on a hook by the door. Check the pocket for a key.
  • Torn Blueprint: On the large drafting table. It's a key piece of the puzzle.

Back Office

  • Locked Safe: Use the key from the overalls to open the filing cabinet. Inside is a note with the safe combination: 27-91-58.
  • Threatening Letter: Inside the now-unlocked safe.
  • Account Ledgers: Also inside the safe, revealing financial trouble.

Case 3: A Silent Secret

This case revolves around a locked room and a victim who appears to have no external injuries. Observation is critical.

The Bedroom Scene

  • Air Purifier: This is the key. Turn it off to stop the memory loop from resetting. It's on a small table by the window.
  • Diary: On the nightstand. Open it to the last page.
  • Hidden Camera: A very small lens hidden in the smoke detector on the ceiling. You need to look straight up.
  • Poisoned Drink: A glass of water on the nightstand. You must use your scanner to identify the chemical agent.

Unlocking the Computer

  • Password Hint: A sticky note attached to the monitor gives a hint: "Her birthday."
  • Birthday Date: A calendar on the wall has a date circled in red: 08-15-2024. The password is 081524.
  • Deleted Files: Once inside the computer, run a recovery program to find a deleted audio file that serves as the final clue.

Case 4: The Double Agent

Here you investigate a corporate espionage case. The clues are split between a sterile office environment and a more personal living space.

The Office Cubicle

  • Shredded Documents: In the wastebasket. You must pick up the pieces and reassemble them on the desk. This is a mini-game.
  • Encrypted USB Drive: Taped to the underside of the desk drawer. You can't access it yet.
  • Keycard: Hidden inside a hollowed-out book on the bookshelf. The book's title is "The Art of Deception."
  • Suspicious Email: Open on the desktop computer, detailing a secret meeting.

The Server Room

  • Decryption Key: Use the keycard to enter the server room. A terminal in the back has the decryption software. Plug in the USB drive here.
  • Server Access Logs: The same terminal shows unauthorized access from a remote IP address.
  • Hidden Microphone: A small magnetic bug attached to the main server rack, near the bottom.
Annotated diagram of the office in Case 4, pointing out all hidden clue locations.

Annotated diagram of the office in Case 4, pointing out all hidden clue locations.

Case 5: The Lab Rat

This investigation takes place in a high-tech laboratory. The environment is complex, with multiple stations and pieces of equipment to inspect.

Main Laboratory

  • Broken Test Tube: On the floor near Station 3. Scan it to identify a foreign biological agent.
  • Contaminated Sample: In the centrifuge. The lid is open. You need to scan the sample inside.
  • Security ID Badge: Has fallen behind a row of computers. Belongs to another scientist.
  • Whiteboard Notes: A complex chemical formula is written on the main whiteboard. Photograph this with your tool.

The Victim's Research Station

  • Personal Datapad: On the desk. It contains research notes and a series of personal logs that reveal a professional rivalry.
  • Unauthorized Experiment Log: You need to solve a simple puzzle on the datapad's screen to unlock a hidden folder containing this log.
  • Genetic Sequencer: The screen shows the results of the last sequence run, which does not match the authorized project parameters.

Case 6: The Collector

This case is set in an antique shop, a cluttered environment where clues are easily mistaken for simple set dressing. Methodical searching is the only way to succeed.

  • Forged Painting: One of the paintings on the wall is a fake. Use your scanner's multispectral mode to reveal the underlying sketch, which is a map.
  • Grandfather Clock: The time is stopped at the moment of death. Open the clock face and retrieve a hidden key from behind the hands.
  • Music Box: On a high shelf. Use the key from the clock to open it. Inside is a coded message.
  • Antique Ledger: On the main counter. The last entry is a massive sale to an anonymous buyer, but the payment was never registered.
  • Hidden Compartment: The map from the painting corresponds to a section of the floorboards. Find the loose board and pry it open to find the murder weapon.
Comic grid showing the 4 steps to finding the murder weapon in Case 6.

Comic grid showing the 4 steps to finding the murder weapon in Case 6.

Case 7: The Inheritance

A domestic dispute turned deadly. This case is heavy on personal items and digital trails.

  • Last Will and Testament: On the lawyer's desk, with a section highlighted that has been recently amended.
  • Fountain Pen: The murder weapon. It's on the floor, but it has been modified with a poison needle. Scan it closely.
  • Muddy Footprints: Leading from the open balcony door. Scan them to get a shoe size and brand.
  • Tablet Device: Contains a record of a heated argument via a messaging app between the two primary heirs.
  • Deleted Voicemail: Access the victim's phone and run a recovery utility to find a deleted message from the killer, left moments after the crime.

Case 8: The Insider

The penultimate case brings the conspiracy into focus. You're investigating a fellow agent, and the clues are digital and deeply hidden.

The Agent's Apartment

  • Burner Phone: Hidden in the water tank of the toilet. You'll need to lift the lid to find it.
  • Go-Bag: A backpack hidden under the bed, containing cash, a fake passport, and an encrypted hard drive.
  • Hidden Wall Safe: Behind a picture frame. The code is found by noticing the dates highlighted on three different calendars around the room: 12-07-26.
  • Signal Jammer: An active device on the bookshelf, which you must disable to access the hard drive's contents.

The Hard Drive

  • Inside the safe is a terminal. Plug the encrypted hard drive in here.
  • Decryption Puzzle: Solve the logic puzzle on the screen to unlock the drive.
  • The Master Plan: The drive contains the full conspiracy details: names, targets, and the mastermind's identity, serving as the final, critical clue.

Case 9: The Mastermind

The final confrontation. This case has fewer, but more significant, clues that tie the entire narrative together. It's less about finding objects and more about making connections.

  • The Mastermind's Terminal: You must access their central computer. The password is the name of the very first victim from Case 1.
  • The M.E. Protocol's Origin: A file on the terminal detailing the true purpose of the technology.
  • The Kill Switch Code: A sequence of numbers that can disable the entire M.E. network. It's the only way to stop the villain.
  • Final Confession: The last clue is an audio log recorded by the mastermind, explaining their motives. Triggering this log initiates the final sequence of the game.

Frequently Asked Questions

Do I need to find every clue to finish a case?

No, you can complete a case by finding just enough clues to make a final deduction. However, finding all clues is the only way to achieve the highest score (S-Rank) and see the full memory reconstruction.

What happens if I miss a clue in Forensic M.E. Protocol?

If you miss a clue, you simply won't get a 100% completion rating for that case. There is no way to go back into a memory once you have finalized your report, so you must be thorough on your first pass.

How many cases are in Forensic M.E. Protocol?

The game consists of nine distinct cases that follow a single overarching narrative.

Is finding all clues required for the true ending?

Yes. The game's final ending sequence is only slightly altered, but the full context and epilogue are reserved for players who have achieved an S-Rank on all nine cases, which requires finding every single clue.

The Final Deduction

Forensic M.E. Protocol rewards meticulous players. Each memory fragment is a breadcrumb leading not just to the solution of a single case, but to the heart of a much larger conspiracy. By using this guide, you can ensure that no stone is left unturned and no memory is left incomplete. The full picture is only available to those who are willing to look at every angle and inspect every last piece of evidence.