This complete FORENSIC - M.E. Protocol all cases walkthrough provides the step-by-step solutions, evidence locations, and puzzle codes for every investigation. From the tutorial case of "The Silent Starlet" to the final conspiracy of "The Chimera Protocol," this guide details the critical path to a 100% completion rate and the game's elusive true ending. We'll cover every piece of evidence, every lab sequence, and every deduction needed to close the book on all four core cases.
Your primary tools are the Multi-spectrum Evidence scanner (M.E.), your autopsy kit, and the Chronos timeline software. Success depends on meticulous observation and connecting seemingly unrelated data points. Missing a single piece of scannable evidence can lock you out of the best conclusion, so follow each step carefully.
Case 1: The Silent Starlet
This introductory case serves as the game's tutorial, teaching you the core mechanics of crime scene investigation and lab analysis. The victim is Anya Petrova, a rising actress found deceased in her high-security penthouse. The solution is straightforward, but finding all evidence is crucial for later achievements.
Crime Scene: Orchid Tower Penthouse
Your first objective is to perform a preliminary sweep of the area before interacting with the body. Do not touch the body until all environmental evidence is tagged.
- Scan the Entryway: Immediately scan the digital lock on the front door. You'll find it was forced with a high-energy EMP device, logged as Evidence #01: Damaged Security Panel. This immediately refutes the initial theory of a clean entry.
- Living Room Clues: Locate the overturned wine glass near the sofa (Evidence #02: Overturned Glass). A close-up scan reveals trace amounts of a fast-acting sedative. On the coffee table, find the victim's personal datapad (Evidence #03: Anya's Datapad). It's password-protected for now.
- Examine the Victim: Now, approach Anya Petrova's body. Scan her neck to find a minuscule puncture wound (Evidence #04: Puncture Wound). Scan her right hand to find fabric fibers that don't match her clothing (Evidence #05: Foreign Fibers).
Annotated Diagram of the Orchid Tower Penthouse crime scene evidence locations.
Lab Analysis & Deduction
Back at the M.E. lab, you'll process the collected evidence. This part of the case is linear and introduces you to the analysis minigames.
- Toxicology: Analyze the sedative from the wine glass. The report confirms it's a rare, custom-synthesized neurotoxin, not a common sedative.
- Data Forensics: Crack the password on Anya's datapad. The solution is her pet's name, found on a photo frame in the living room: LUNA2024. Read the emails to uncover a series of threatening messages from her agent, Julian Croft.
- Material Analysis: The foreign fibers from Anya's hand are a match for a specific brand of cashmere coat. A database search links this brand to a recent purchase by Julian Croft.
With this, the timeline in your Chronos software becomes clear. Julian arrived, disabled the lock, drugged the wine, and administered the fatal dose via a hidden syringe mechanism (a ring or pen). Drag the Threatening Emails, Foreign Fibers, and Damaged Security Panel onto Julian Croft's profile to complete the deduction and close the case.
Case 2: The Dockside Deception
This case ramps up the difficulty, introducing red herrings and the need to cross-reference financial documents. The victim is Marco "The Bull" Leone, a union boss found in a locked shipping container at Pier 4. The cause of death is a single gunshot wound, but the real mystery is how the killer got in and out.
Crime Scene: Pier 4 Storage
The container is sealed from the inside, suggesting suicide. Your job is to prove it was murder.
- The Body: Examine Marco's body. The gunshot wound is to the chest (Evidence #06: GSW Chest). A ballistic analysis in your M.E. scanner reveals the bullet's trajectory is from a sharp downward angle, inconsistent with a self-inflicted wound.
- The Weapon: A standard-issue revolver lies near his hand (Evidence #07: Revolver). A scan shows Marco's fingerprints, but also a faint, wiped-down print underneath. It's too degraded to ID, but proves someone else handled the weapon.
- The Environment: The key clue is high on the container wall. Activate your M.E. scanner's thermal mode and look up. You'll spot a recently replaced ventilation grate (Evidence #08: Disturbed Vent Grate). Scanning the grate reveals microscopic metal shavings that don't match the container's steel.
Unraveling the Manifests
Your lab work will focus on tracing the origin of the metal shavings and digging into Marco's financials, which are linked from his office computer.
- Metallurgy: The shavings from the vent are a titanium-tungsten alloy, used in high-end cutting tools. This is your murder weapon, not the gun.
- Financial Records: Marco's computer reveals a shell corporation, "Oceanic Imports," used for laundering money. Cross-referencing shipping manifests shows that Oceanic Imports had a container delivered to Pier 4 an hour before Marco's time of death. The manifest was signed by his second-in-command, Silas "The Weasel" Vance.
- The Red Herring: You'll find threatening letters from a rival union leader. This is a dead end designed to waste your time. The financial data is the real key.
Infographic showing the suspect and evidence connections in The Dockside Deception.
The Conclusion: Pinning Silas Vance
The pieces now fit. Silas lured Marco to the container under the pretense of a deal. He was already inside the adjacent Oceanic Imports container, from which he had cut a small hole through the shared wall (where the vent was). He shot Marco from above, then used a tool to place the gun in Marco's hand and bolt the container from the inside. Your timeline should show Silas's manifest signature, the delivery of the adjacent container, and the impossible bullet trajectory. Present these three facts to corner Silas for the confession.
Case 3: The Gilded Cage
This is a classic locked-room mystery. Eccentric art collector Alistair Moreau is found dead in his panic room, which is sealed from the inside. The cause of death is poisoning, but there's no delivery system in the room. This case tests your environmental observation skills to their limit.
The Locked Room: Moreau Estate
The panic room is small and contains only a chair, a desk, and a large painting. The air is still, and there are no syringes or glasses.
- The Victim: Alistair has no injection marks. A preliminary scan shows his vital signs ceased approximately 12 hours ago. The key is to scan his lungs, which reveals trace amounts of aerosolized poison (Evidence #09: Aerosolized Toxin).
- The Environment: The room's ventilation system is a closed loop, meaning the poison had to originate inside. Switch your M.E. scanner to the atmospheric filter. You'll detect a higher concentration of the toxin near the central air vent on the ceiling (Evidence #10: Contaminated Air Vent).
- The Painting: The large oil painting, titled "Chronos Devouring His Son" (1888), is the only interactive object. Scan it. The M.E. scanner will note that the paint composition is unusual, containing trace elements of non-artistic materials. This is your hint.
Comic Grid showing the four steps to solve The Gilded Cage vent puzzle.
Cracking the Safe Combination
This case's central puzzle is figuring out how the poison was delivered. Interacting with the air vent reveals it's locked by a hidden mechanism. The painting holds the key.
- UV Light: Switch your M.E. scanner to the UV spectrum and shine it on the painting. Numbers and symbols will appear over the paint. Near the bottom, you'll see a sequence: A -> 1, B -> 8, C -> 8, D -> 8.
- The Desk: On the desk is a small, ornate box with a four-digit keypad. This is the control for the vent. The code is derived from the painting's date: 1888. Entering this code opens a hidden compartment behind the vent.
- The Delivery System: Inside the compartment, you find a pressure-activated canister (Evidence #11: Discharged Canister) connected to the ventilation system. It was set on a timer. The killer activated it remotely or set the timer before Alistair entered the room, then Alistair sealed the door himself, creating the locked-room paradox.
The final piece of the puzzle is linking the canister to a suspect. The canister's manufacturing ID is traceable to a chemical supply company owned by Moreau's estranged son, who recently had his inheritance revoked. The motive is clear.
Case 4 & The True Ending: The Chimera Protocol
The final case ties everything together. After solving the Moreau case, you're alerted to a pattern: the custom sedative from Case 1, the cutting tool alloy from Case 2, and the aerosolized toxin from Case 3 were all developed by one shadowy R&D firm, OmniGen.
This case is less about a single crime scene and more about connecting the dots in your Chronos software. You'll revisit evidence from all previous cases, looking for a hidden signature in the chemical compositions and manufacturing logs. This signature is the mark of a single rogue chemist—the Chimera—who has been selling bespoke murder weapons to the highest bidders, including Julian Croft and the Moreau son.
Requirements for the True Ending
To unlock the true ending, where you expose the entire conspiracy and the Chimera, you must have a 100% evidence collection rate across the first three cases. If you missed any piece of evidence, you will be forced into a premature, unsatisfying ending where you can only convict the Chimera's clients, not the mastermind.
Critical Evidence Checklist:
- Case 1: All 5 pieces of evidence from the Orchid Tower Penthouse.
- Case 2: The Disturbed Vent Grate is the most commonly missed clue. You must scan it before leaving the scene.
- Case 3: The Discharged Canister behind the vent. You must solve the painting puzzle to access it.
If you have all the evidence, a new node will appear in your Chronos software: "Cross-Case Analysis." This initiates the final sequence. You'll trace OmniGen's internal network, expose the Chimera's identity (Dr. Aris Thorne), and present the airtight case to your superiors.
Poster comparing the Standard and True Endings for The Chimera Protocol.
The Final Choice: Protocol or Justice
In the final confrontation, you learn that Dr. Thorne's work was secretly sanctioned by a rogue element within your own agency. You are given a choice:
- The Standard Ending: Follow protocol. You leak the evidence against the clients (Croft, Vance, etc.) but the files on OmniGen and the Chimera are buried. The conspiracy continues. You get the "Case Closed" achievement.
- The True Ending: Defy orders. You leak the entire investigation to the media, exposing OmniGen, the Chimera, and your agency's complicity. This destroys your career but brings the entire network to justice. You get the "The Whole Truth" achievement.
Frequently Asked Questions
How many cases are in FORENSIC - M.E. Protocol? There are four main cases: The Silent Starlet, The Dockside Deception, The Gilded Cage, and the final overarching case, The Chimera Protocol.
What is the safe code in The Gilded Cage? The code for the keypad that opens the vent compartment is 1888, derived from the date on the painting in the panic room.
Am I locked out of the true ending if I miss evidence? Yes. You must collect every single piece of scannable evidence in the first three cases to unlock the final analysis sequence required for the true ending. If you miss even one, you will get the standard, incomplete ending.
Where is the last piece of evidence in Case 2? The most commonly missed piece of evidence in "The Dockside Deception" is the Disturbed Vent Grate. It's located high on the wall inside the shipping container and is best seen using the M.E. scanner's thermal vision.
Final Analysis
FORENSIC - M.E. Protocol rewards thoroughness above all else. The path to its true conclusion isn't about complex action sequences but about a dedication to the process—sweeping every room, scanning every object, and reading every file. Rushing a crime scene is the surest way to miss a critical link, forcing you to settle for a lesser ending where justice is only partially served. Take your time, trust your tools, and leave no stone unturned.