The best relics in 33 Immortals are those that grant scaling power, run-saving utility, or build-defining synergies. This 33 Immortals best relics tier list places items like the Phoenix Plume and Golden Fleece firmly in S-Tier because they consistently enable successful runs by either cheating death or providing infinitely scaling damage, far outpacing relics that offer only minor stat boosts.
This guide moves beyond a simple ranking. We'll dissect why certain relics are meta-defining, explore powerful combinations that trivialize boss fights, and help you evaluate which relic choice is right for your current build, even if it means picking a C-Tier item for a specific, desperate situation.
What Makes a Relic S-Tier?
In a cooperative roguelike like 33 Immortals, a relic's value isn't just about personal power—it's about how it contributes to the success of the entire 33-player raid. Our ranking prioritizes relics based on four key factors:
- Run-Defining Potential: Does this relic fundamentally change how you play the rest of the run? S-Tier relics do.
- Scaling: Does the relic's power grow exponentially with other relics, gold, or stats? The best relics multiply your power, they don't just add to it.
- Consistency: How often is this relic a must-pick? An S-Tier relic is almost never the wrong choice, regardless of your weapon or build.
- Raid Impact: Does this relic help you or your allies survive and deal more damage during the chaotic final boss encounters? A second life from a Phoenix Plume benefits the entire raid.
In contrast, C-Tier relics are often highly situational or provide a simple, flat bonus that gets quickly overshadowed. They can be useful to plug a hole in your build, but you should aim to replace them as soon as a better option appears.
S-Tier: The Pillars of Ascension
These are the relics you pray to see. Finding one of these early can single-handedly set your run up for a triumphant Ascension against Lucifer. They are powerful enough to justify building your entire strategy around them.
- Phoenix Plume: The undisputed king of relics. A free revive is the most powerful effect in any roguelike, period. It erases a fatal mistake, letting you learn boss patterns without consequence. In a raid setting, having multiple players with a Plume is a massive safety net that dramatically increases the odds of success. There is no situation where you do not take this.
- Golden Fleece: The ultimate scaling relic. It converts your gold into raw power, a bonus that grows infinitely throughout the run. This encourages a high-risk, high-reward playstyle where you prioritize wealth. When combined with other gold-synergy relics, the Golden Fleece can produce absurd damage numbers by the final few circles of Hell.
- Hephaestus' Hammer: Guarantees an upgrade for your current weapon. This is incredibly potent in the early stages, as it lets you immediately boost your core damage source to a higher rarity. A rare or epic weapon in the first few skirmishes creates a snowball effect, allowing you to clear enemies faster, earn more rewards, and secure a power advantage that carries you through the entire run.
A-Tier: Powerful and Reliable Staples
A-Tier relics aren't quite as game-breaking as the S-Tier pantheon, but they are incredibly solid picks that will significantly improve any build. You are always happy to see these, and they often form the core of a strong, synergistic loadout.
- Hermes' Sandals: Mobility is life. More movement speed means an easier time dodging projectiles, repositioning during boss fights, and escaping overwhelming swarms of enemies. While it doesn't directly boost your damage, the survivability it provides is invaluable and makes every other aspect of the game easier.
- Divine Protection: A straightforward but highly effective defensive tool. Flat damage reduction becomes increasingly valuable in later stages where enemy attacks can shred your health bar in seconds. This relic provides a consistent layer of toughness that can be the difference between surviving a big hit and being sent back to the start.
- Artemis' Quiver: A build-defining relic specifically for bow users. The extra projectiles dramatically increase your area-of-effect damage and overall DPS. If you are using a bow, this relic instantly becomes S-Tier for your build. For any other weapon, it's useless, which is the only thing holding it back from the highest tier.
33 Immortals in-game screenshot
B & C-Tier: Niche, Situational, and Early-Game Fillers
It's easy to dismiss lower-tier relics, but they have their place. These items are best used to solve a specific problem or to provide a small boost until a better option comes along. Sometimes, the right C-Tier relic is more valuable for a specific boss fight than a generic A-Tier one.
B-Tier: Strong Under the Right Circumstances
These relics require other pieces to function at a high level or are only effective in certain builds. Pandora's Box, for example, which gives you a chance at extra relic choices, is pure RNG. It can be incredible if it triggers multiple times, but it can also do nothing. Midas' Touch, which grants bonus gold on kill, is a fantastic enabler for a Golden Fleece build but is merely decent on its own.
C-Tier: Better Than Nothing
This is where the most basic relics live. Charon's Obol, which simply grants a lump sum of gold, is a prime example. It's nice to have early on, but it provides no scaling and is completely outclassed by other gold-generating relics. Likewise, Ambrosia, which provides a one-time heal, can be a lifesaver in a pinch, but relics that prevent damage in the first place, like Divine Protection, offer far more long-term value.
33 Immortals in-game screenshot
Relic Combos That Break the Game
The true path to power in 33 Immortals lies in synergy. A single S-Tier relic is great, but a combination of A and B-Tier relics that multiply each other's effects is even better. Here are a few game-winning combos to look for.
The Gold-Blooded God
This build aims to turn wealth into unstoppable power. It's a greedy playstyle that can feel weak at the start but becomes an unstoppable force if you assemble the key pieces.
- Core Relic: Golden Fleece (S-Tier). Your damage scales with gold.
- Enabler: Midas' Touch (B-Tier). Massively increases your gold income, directly fueling the Golden Fleece.
- Payoff: Pandora's Box (B-Tier). With your vast wealth, you can afford to buy extra relics from shops. Pandora's Box gives you a chance to get even more choices, accelerating your build into overdrive.
The Untouchable Skirmisher
This combo focuses on pure mobility and invincibility, allowing you to dance through the most chaotic fights without taking a scratch. It's particularly effective with melee weapons that have dash-strike attacks.
- Core Relic: Hermes' Sandals (A-Tier). The foundation of your speed.
- Synergy Piece: Elusive Cloak (A-Tier, hypothetical name for a dash-invincibility relic). Grants brief invulnerability after a dash.
- Enhancer: Chrono-Amulet (B-Tier, hypothetical name for a dash-charge relic). Grants additional dash charges or reduces their cooldown. With these three, you can spend more time invincible than vulnerable.
33 Immortals in-game screenshot
Frequently Asked Questions about Relics
How do you get Legendary Relics? Legendary (orange) rarity relics are the most powerful in the game. They are typically found by defeating major bosses, completing challenging optional encounters (like the treasury rooms), or by being purchased in the final shop before Lucifer for a very high price.
Can you upgrade Relics? No, you cannot directly upgrade the rarity of a relic you are already holding. However, the Hephaestus' Hammer relic effectively serves this function for your weapon, and you can occasionally find higher-rarity versions of relics in later stages of a run.
What's the worst Relic in 33 Immortals? While context matters, Charon's Obol is often considered the weakest. Its one-time gold infusion is quickly dwarfed by the scaling income from other relics like Midas' Touch or the raw power from Golden Fleece, making it a dead-end choice in the long run.
Should I focus on offense or defense with my Relics? Early in a run, prioritize offense to speed up clears and earn rewards faster. As you approach the final boss, securing at least one strong defensive relic—like Divine Protection or the ultimate defense, a Phoenix Plume—is critical. A balanced build is almost always better than a pure glass cannon.
Final Judgment
Mastering the relic system is key to consistently achieving Ascension in 33 Immortals. Don't just grab the highest rarity item offered. Think about your current weapon, your existing relics, and the challenges ahead. The player who can build a synergistic machine out of A and B-Tier parts will always outperform the one who gets lucky with a single, unsupported S-Tier relic. Focus on scaling, build-defining synergies, and a single cheat-death mechanic, and you'll escape damnation in no time.